I installed ResilientWare’s MouseTutor on the kids’ computer so I could disable the right button. While
playing the Curious George flash games at pbskids.org, Miles was
frequently hitting the right button which would popup the flash player
menu which he didn’t know what to do with and would click randomly on a
menu item. Sometimes it would reload the game, other ones essentially
kill it by backing up. The only trick is the software remembers it’s
running and whether the mouse is in one or two button mode. So don’t
change the registry or add it to your Start menu -> Programs ->
Startup folder or you’ll get two copies running the next time you log
in.

This wasn’t a problem with the KidzMouse we had which did the same thing in the driver but that was a mechanical mouse with a wire which ended up being more of an issue for them than I expected. Mostly the wire, actually so the wireless KidzMice weren’t the answer. I replaced it with a boring logitech laptop mouse — small for little hands, wireless and optical.